Case Fatality Rate (CFR)

An estimate of the risk of mortality from a contagious disease. The CFR is calculated by dividing the number of deaths caused by disease by the number of cases of that disease in a given time period. The CFR is time and location-dependent, and many different factors can influence the CFR, such as speed of diagnosis of cases, health system capacity, age and other demographic characteristics, among others. For COVID-19, estimates of the CFR have varied; in China, CFR estimates by province have ranged from <1% to 5.8%. (Sources: CDC/Lipsitch et. al./WHO)